Misaki Kanon, a young woman who came to the big city with dreams of becoming a singer. At first everything goes well, she falls in love and works towards her dream. But then her boyfriend betrays her and Kanon loses her faith in people and sight of her dream. Once upon a time she sang the song of prayer as a small child in a remote mountain village where the Daimajin rests, now she has to regain her song to find herself and maybe save the world, too. A mysterious man from the village is searching for her so that she may help him and his comrades when the time comes. Meanwhile strange creatures start appearing in the city, possessing humans and causing trouble.